High vs Low

High- slang euphoric state, esp. drug-induced (am on a high). intoxicated by alcohol or esp. drugs.That is one of the meaning of the word High from OXford Pocket Dictionary Ver March 1994 (just to get offical).The meaning usually depends on the context of its usage as all of you will know.
Low is what is opposite to being high. E.g. High being a chill state where "the grass is green and the girls are pretty* (lyrics from the beautiful song paradise city by guns n roses). Whereas low being a state where you have to watch a movie like "17 again", only to find out it has a sequel too.
Thats one example, Yes there are countless other examples that can be quoted to pronounce the true nature of a high or a low. You can be high on power, but low on self-esteem, high on life, low on sincerity. One cannot judge, but with each high theres surely some advantage or for the matter of argument downsides aswell. Low has its own set of compensations.
I'll like to know, what an average reader like you tend to think about the topic in hand?